Protopic (Tacrolimus)

Protopic Review

Use Protopic only to treat eczema that has been diagnosed by a doctor.

Buy Protopic in a reliable US Online Pharmacy
FedEx Next Day Delivery

Protopic Drug Class and Mechanism

Tacrolimus is chemically known as a macrolide. It reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP-12 (FK506 binding protein) creating a new complex. This FKBP12-FK506 complex interacts with and inhibits calcineurin thus inhibiting both T-lymphocyte signal transduction and IL-2 transcription. Although this activity is similar to cyclosporin, studies have shown that the incidence of acute rejection is reduced by tacrolimus use over cyclosporin.

Protopic Uses

Protopic is an ointment containing Tacrolimus, a macrolide immunosuppressant produced by Streptomyces tsukubaensis. Protopic or Tacrolimus ointment is an immunomodulatory drug, which modulates or affects the immune system, and reduces the activity of immune system, benefitting atopic eczema condition that is aggravated by the hyperactivity or hypersensitivity of immune system. Thus Protopic Ointment is used to treat eczema (atopic dermatitis).Protopic is for adults and children age 2 years and older. Protopic may be used for short or intermittent long periods of treatment, as directed by your doctor. You can use it on all affected areas of your skin, including your face and neck

Protopic Side Effects

The most common side effects of Protopic include stinging, soreness, a burning feeling, or itching of the skin treated with Protopic. These side effects are usually mild to moderate, are more common during the first few days of treatment, and typically lessen as your skin heals. Less common side effects include acne, swollen or infected hair follicles, headache, increased sensitivity of the skin to hot or cold temperatures, or flu-like symptoms such as stuffy nose. Some people may get skin tingling, upset stomach, herpes zoster (chicken pox or shingles), or muscle pain. While you are using Protopic, drinking alcohol may cause the skin or face to become flushed or red and feel hot. Call your doctor if side effects continue or become a problem.

Protopic Pregnancy

Protopic Overdose

PROTOPIC Ointment is not for oral use. Oral ingestion of PROTOPIC Ointment may lead to adverse effects associated with systemic administration of tacrolimus. If oral ingestion occurs, medical advice should be sought.

Protopic More Information

Do not use Protopic for a condition for which it was not prescribed. If you have any concerns about Protopic, ask your doctor. Your doctor or pharmacist can give you information about Protopic that was written for health care professionals.